The age-old war between felines and canines is blown into a high-tech battle of epic proportions when scientist Jeff Goldblum develops a cure to human allergies to dogs. It becomes the duty of Goldblum's family puppy and his covert canine buddies to guard the vaccine from a cat army out to steal it and take over the world. Alec Baldwin, Charlton Heston, Jon Lovitz, Tobey Maguire and Susan Sarandon lend their voices to the animal antagonists.
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