The year is 1930. America is gripped by the Depression. But in a time of poverty and despair, two men refused to give up hope. Lennie (John Malkovich), feeble minded and naive and George (Gary Sinise), who is clever and resourceful, are a strange couple at first sight. Nevertheless they gain strength from their friendship, as they travel from town to town. Hungry and broke they arrive at the Tyler Ranch where they find work and shelter. But their peace is shattered by the arrival of a beautiful but bored young woman (Sherilyn Fenn), a woman who turns Lennie's hitherto simple life upside down - with shocking, fateful consequences. 'Of Mice and Men' is a powerful and unforgettable adaptation of one of America's greatest novels, by John Steinbeck.
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